6-Methyl-1,2,3,4-tetrahydroquinoline → 1-(3,4-Dimethoxybenzoyl)-2-methyl-4-(6-methyl-1,2,3,4-tetrahydroquinolin-1-yl)-1,2,3,4-tetrahydroquinoline

Participants

Reaction Steps

Starting with cis-1-(3,4-dimethoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol (500 mg, 1.53 mmol) prepared in Reference Example 1 and 6-methyl-1,2,3,4-tetrahydroquinoline (676 mg, 4.59 mmol), the same procedure as shown in Example 1 was repeated to give the titled compound (117 mg, yield: 18%) as a white crystal. (cis:trans=1.6:1)

Provenance & Evidence