Ethyl 5-[(1,2,3,4-tetrahydro-6-quinolinyl)oxy]pentanoate → Ethyl 5-[[1-[1-(3,4-dimethoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinyl]-1,2,3,4-tetrahydro-6-quinolinyl]oxy]pentanoate

関与物質

反応手順

Starting with cis-1-(3,4-dimethoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol (1.0 g, 3.05 mmol) prepared in Reference Example 1 and ethyl 5-[(1,2,3,4-tetrahydro-6-quinolinyl)oxy]pentanoate (487 mg, 3.66 mmol), the same procedure as shown in Example 1 was repeated to give the titled compound (760 mg, yield: 42%) as a colorless oil. (cis:trans=1:1.2)

情報源と証拠