N-(1,2,3,4-tetrahydro-6-quinolinyl)butanamide → N-[1-[1-(3,4-Dimethoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinyl]-1,2,3,4-tetrahydro-6-quinolinyl]butanamide

Participants

Reaction Steps

Starting with cis-1-(3,4-dimethoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol (800 mg, 2.44 mmol) prepared in Reference Example 1 and N-(1,2,3,4-tetrahydro-6-quinolinyl)butanamide (1.33 g, 6.1 mmol), the same procedure as shown in Example 1 was repeated to give the titled compound (463 mg, yield: 36%) as a colorless oil. (cis:trans=1:1.3)

Provenance & Evidence