Potassium Iodide → HCID 22066270, compound

Participants

Reaction Conditions

Reaction Steps

6-bromo-biphenyl-3,3′-diol (5.92 g, 22.43 mmol) prepared in Example 2, 1-octylbromide, potassium carbonate (18.60 g, 134.56 mmol) and potassium iodide (3.72 g, 22.43 mmol) were dissolved in dimethylformamide (60 ml), followed by heating for about 24 hours at about 150° C. After cooling to room temperature, distilled water was added to the resultant and stirred for about 10 minutes, followed by filtering three times with hexane, washing three times with distilled water, drying with sodium sulfate. Then, the hexane was concentrated under reduced pressure. Purification by silica gel chromatography using 4% dichloromethane in hexane gave 2-bromo-5,3′-bis-octyloxy-biphenyl corresponding to the compound III of the reaction scheme 1 (Yield: 6.36 g, 58.1%), R1 and R2 in the formula of the compound III being each independently octyl. The product was identified through the NMR spectrum and element analysis that it had the identical structure with the compound III.

Provenance & Evidence