HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[(2-{[(Tert-butoxy)carbonyl]amino}ethyl)sulfanyl]propanoic acid → [2-(3-{4-[(4As,8ar)-4-(3,4-dimethoxy-phenyl)-1-oxo-4a,5,8,8a-tetrahydro-1h-phthalazin-2-yl]-piperidin-1-yl}-3-oxo-propylsulfanyl)-ethyl]-carbamic acid tert butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[(2-{[(Tert-butoxy)carbonyl]amino}ethyl)sulfanyl]propanoic acid | HCID 22337174 | — |
| Reactant | (4aS,8aR)-4-(3,4-Dimethoxy-phenyl)-2-piperidin-4-yl-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one | HCID 68878852 | — |
| Reactant | (4-{4-[(4aS,8aR)-4-(3,4-Dimethoxy-phenyl)-1-oxo-4a,5,8,8a-tetrahydro 1H-Phthalazin-2-yl]-piperidin-1-yl}-4-oxo-butyl)-carbamic Acid Tert Butyl Ester | HCID 86759810 | — |
| Product | [2-(3-{4-[(4As,8ar)-4-(3,4-dimethoxy-phenyl)-1-oxo-4a,5,8,8a-tetrahydro-1h-phthalazin-2-yl]-piperidin-1-yl}-3-oxo-propylsulfanyl)-ethyl]-carbamic acid tert butyl ester | HCID 91343091 | — |
Reaction Steps
Prepared from 12 mmol of 3-(2-tert-butoxycarbonylamino-ethylsulfanyl)-propionic acid and 10 mmol of compound 5c as described for compound 5b. M. p. 132-134° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06933296B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-f975ee5cbf2847f7a691b5f31c4b1ffd |
| Source note | uspto-grants-2005_08 |