HRID585532

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID69558

Pentafluorobenzaldehyde

C7HF5O

结构：CCOC(=O)[C@H](Cc1ccc(OCCc2nc(-c3ccc(C)cc3)oc2C)cc1)NCc1ccc(F)cc1

HCID12149026

未命名化合物

PRODUCTS

生成物

结构：COC(=O)[C@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)NCc1c(F)c(F)c(F)c(F)c1F

HCID131725071

未命名化合物

PROCEDURE

实验过程

In the same manner as in Example 7, 433.0 mg of the title compound was obtained as colorless oil from 591.2 mg of Referential Compound 3 and 250 μL of pentafluorobenzaldehyde.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-67037af6163c42c3b87c648363bd3c51
来源数据集: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06933309B2
来源说明: uspto-grants-2005_08

反应 SMILES

[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][C:10](C)=[CH:9][CH:8]=2)=[N:4][C:3]=1[CH2:14][CH2:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([CH2:23][C@H:24]([NH:30]CC2C=CC(F)=CC=2)[C:25]([O:27][CH2:28]C)=[O:26])=[CH:19][CH:18]=1.[F:39][C:40]1[C:45]([CH:46]=O)=[C:44]([F:48])[C:43]([F:49])=[C:42]([F:50])[C:41]=1[F:51]>>[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[N:4][C:3]=1[CH2:14][CH2:15][O:16][C:17]1[CH:18]=[CH:19][C:20]([CH2:23][C@H:24]([NH:30][CH2:46][C:45]2[C:40]([F:39])=[C:41]([F:51])[C:42]([F:50])=[C:43]([F:49])[C:44]=2[F:48])[C:25]([O:27][CH3:28])=[O:26])=[CH:21][CH:22]=1