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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 585533Generated: October 30, 2026

2-Chlorobenzaldehyde → Methyl(S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-(2-chlorobenzylamino)propionate

https://huagongshe.com/reaction/585533

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorobenzaldehydeHCID 6996—
ReactantEthyl(S)-3-[4-[2-[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]ethoxy]phenyl]-2-(4-fluorobenzylamino)propionateHCID 12149026—
ProductMethyl(S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-(2-chlorobenzylamino)propionateHCID 69731883—

Reaction Steps

In the same manner as in Example 7, 466.5 mg of the title compound was obtained as colorless oil from 609.3 mg of Referential Compound 3 and 230 μL of 2-chlorobenzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06933309B2
Source datasetuspto-grants-2005_08
ORD IDord-b849f9d265034cf0a0138f9dc2b14eca
Source noteuspto-grants-2005_08