HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminopyridine → HCID 22337421, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminopyridine | HCID 1727 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 22337460 | HCID 22337460 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 22337421 | HCID 22337421 | 33.4% |
Reaction Steps
By a similar reaction operation as in Starting Material Synthetic Example 7 using 5-(benzyloxycarbonylamino)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (2.50 g), thionyl chloride (2.75 g), 4-aminopyridine (724 mg) and triethylamine (1.55 g), the objective 5-(benzyloxycarbonylamino)-N-(4-pyridyl)-5,6,7,8-tetrahydronaphthalene-2-carboxamide (1.03 g) was obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06933305B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-ba4e4b5592604d9c81bb3f64fced2d6e |
| Source note | uspto-grants-2005_08 |