HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminopyridine → HCID 59089453, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminopyridine | HCID 1727 | — |
| Reactant | 2-Chloro-1-methylpyridinium iodide | HCID 167069 | — |
| Reactant | HCID 59089475 | HCID 59089475 | — |
| Product | HCID 59089453 | HCID 59089453 | 74.6% |
Reaction Steps
By a similar reaction operation as in Starting Material Synthetic Example 53 using (S)-4-(tert-butoxycarbonylamino)-6-methoxythiochromane-7-carboxylic acid (300 mg), 4-aminopyridine (83.3 mg) and 2-chloro-1-methylpyridinium iodide (271 mg), the objective (S)-4-(tert-butoxycarbonylamino)-6-methoxy-N-(4-pyridyl)thiochromane-7-carboxamide (274 mg) was obtained as a pale-red amorphous solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06933305B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-07db32aeed6d4adb8478ae97a692f9ab |
| Source note | uspto-grants-2005_08 |