Hydroquinone → HCID 22338334, compound

Participants

Reaction Conditions

Reaction Steps

In the solution of 220 g(2 mol) of hydroquinone in 500 ml of acetic acid, 107.5 g(1 mol) of dimethylcarbamyl chloride was drop-added for one hour while agitating the solution at 110° C. The mixture was maintained at 110° C. for two hours, and acetic acid was distilled under vacuum. 1 liter of methylene chloride was added to the reaction mixture, and the unreacted excess hydroquinone was filtered and collected (recoverd amount: 110 g, recycled without any purification process). A desired mono N,N-dimethylcarbamyl hydroquinone was obtained by evaporating the residue under vacuum. (Yield: 178.6 g(98%). mp: 144-146° C., 1H-NMR(200 MHz, CDCl3, ppm) 3.05 (d, 6H), 6.59 (d, 2H), 6.80 (br, 1H) 6.82 (d, 2H).

Provenance & Evidence