Benzenemethanamine, 3,4-dichloro- → HCID 22032660, compound

Participants

Reaction Steps

The title compound was prepared using the procedure described in Example 222B using 3,4-dichlorobenzylamine and 2-(5-isoquinolinyl)propanoic acid instead of 4-(trifluoromethoxy)benzylamine and 5-isoquinolinylacetic acid. MS (ESI+) m/z 359 (M+H)+; MS (ESI−) m/z 357 (M−H)−; 1H NMR (DMSO, 300 MHz) δ 1.54 (d, J 7.1, 3H), 4.20 (m, 2H), 4.53 (q, J 7.1, 1H), 7.16 (d, J 8.4, 1H), 7.31 (s, 1H), 7.52 (d, J 8.4, 1H), 7.77 (t, J 7.8, 11H), 7.89 (d, J 6.5, 11H), 8.16 (d, J 8.1, 1H), 8.22 (d, J 6.4, 11H), 8.59 (d, J 6.2, 11H), 8.64 (t, J 5.8, 11H), 9.49 (s, 1H).

Provenance & Evidence