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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 586607Generated: October 26, 2026

1,1,3,3-Tetramethylbutyl isocyanide → [5-(2,4-Dimethyl-phenyl)-imidazo[1,2-b][1,2,4]triazol-6-yl]-(1,1,3,3-tetramethyl-butyl)-amine

https://huagongshe.com/reaction/586607

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1,3,3-Tetramethylbutyl isocyanideHCID 26725—
Reactant2,4-DimethylbenzaldehydeHCID 61814—
ReactantHCID 178418311HCID 178418311—
SolventPerchloric AcidHCID 24247—
Product[5-(2,4-Dimethyl-phenyl)-imidazo[1,2-b][1,2,4]triazol-6-yl]-(1,1,3,3-tetramethyl-butyl)-amineHCID 22335554—

Reaction Steps

Compound 53 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 3-amino-1,2,4-triazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) 1,1,3,3-tetramethylbutylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 2,4-dimethylbenzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06936631B2
Source datasetuspto-grants-2005_08
ORD IDord-bd295fb181c74e6e8f00176956515ca9
Source noteuspto-grants-2005_08