HCID 86595794, compound → HCID 86595803, compound

HRID 586658Notes

Reaction equation

HRID 586658 reaction equation
COC[C@@H]1[C@H](C=O)[C@]1(C)C1C=CC2C(C)(C)CCC(C)(C)C=2C=1.CC12C(C)(C)[C:28]([C:34]([O:36][CH2:37][C@@H:38]3[C@H:40]([CH2:41][O:42]CC)[C@:39]3([CH3:59])[C:45]3[CH:54]=[CH:53][C:52]4[C:51]([CH3:56])([CH3:55])[CH2:50][CH2:49][C:48]([CH3:58])([CH3:57])[C:47]=4[CH:46]=3)=O)(CC1)OC2=O>>[CH2:34]([O:36][CH2:37][C@H:38]1[C@@H:40]([CH:41]=[O:42])[C@@:39]1([CH3:59])[C:45]1[CH:54]=[CH:53][C:52]2[C:51]([CH3:56])([CH3:55])[CH2:50][CH2:49][C:48]([CH3:58])([CH3:57])[C:47]=2[CH:46]=1)[CH3:28]

Participants

3

Reactant 2

HCID 86595794HCID 86595794, compoundHCID 86595801HCID 86595801, compound

Product 1

HCID 86595803HCID 86595803, compoundYield 94%

Procedure

Following a procedure similar to that for the preparation of Intermediate 12a but using Intermediate 9b as the starting material afforded the title compound (36 mg, 94% yield) as a colorless oil:

Sources & evidence

ORD record
ord-7100e450f23942a18f7c4bd9760954c3
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

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