HCID 86595801, compound → HCID 86759824, compound

HRID 586661Notes

Reaction equation

HRID 586661 reaction equation
[CH3:1][O:2][CH2:3][C@@H:4]1[C@H:6]([CH:7]=[O:8])[C@:5]1([CH3:23])[C:9]1[CH:18]=[CH:17][C:16]2[C:15]([CH3:20])([CH3:19])[CH2:14][CH2:13][C:12]([CH3:22])([CH3:21])[C:11]=2[CH:10]=1.CC12C(C)(C)C(C(OC[C@@H]3[C@@H](COC)[C@]3(C)C3C=CC4C(C)(C)CCC(C)(C)C=4C=3)=O)(CC1)OC2=O>>[CH3:1][O:2][CH2:3][C@@H:4]1[C@@H:6]([CH:7]=[O:8])[C@@:5]1([CH3:23])[C:9]1[CH:18]=[CH:17][C:16]2[C:15]([CH3:20])([CH3:19])[CH2:14][CH2:13][C:12]([CH3:22])([CH3:21])[C:11]=2[CH:10]=1

Participants

3

Reactant 2

HCID 86595801HCID 86595801, compoundHCID 86759822HCID 86759822, compound

Product 1

HCID 86759824HCID 86759824, compoundYield 81%

Procedure

Following a procedure similar to that for the preparation of Intermediate 12a but using Intermediate 11a as the starting material afforded the title compound (25 mg, 81% yield) as a colorless oil:

Sources & evidence

ORD record
ord-1431d0afe25b4f2ab654bce515913b64
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

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