HCID 86595802, compound → HCID 131725080, compound

HRID 586663Notes

Reaction equation

HRID 586663 reaction equation
[CH3:1][O:2][CH2:3][C@@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@@:5]1([CH3:31])[C:17]1[CH:26]=[CH:25][C:24]2[C:23]([CH3:28])([CH3:27])[CH2:22][CH2:21][C:20]([CH3:30])([CH3:29])[C:19]=2[CH:18]=1.COC[C@H]1[C@@H](C=O)[C@@]1(C)C1C=CC2C(C)(C)CCC(C)(C)C=2C=1>>[CH3:1][O:2][CH2:3][C@H:4]1[C@@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@:5]1([CH3:31])[C:17]1[CH:26]=[CH:25][C:24]2[C:23]([CH3:28])([CH3:27])[CH2:22][CH2:21][C:20]([CH3:30])([CH3:29])[C:19]=2[CH:18]=1

Participants

3

Reactant 2

HCID 86595802HCID 86595802, compoundHCID 131725081HCID 131725081, compound

Product 1

HCID 131725080HCID 131725080, compoundYield 66%

Procedure

Following a procedure similar to that for the preparation of Compound 16a but using Intermediate 13a as the starting material afforded the title compound (53 mg, 66% yield) as a white solid:

Sources & evidence

ORD record
ord-f3642154e77d41c88e41449c663a2580
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

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