HCID 86595803, compound → HCID 131725082, compound

HRID 586664Notes

Reaction equation

[CH3:1][O:2][CH2:3][C@@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@@:5]1([CH3:31])[C:17]1[CH:26]=[CH:25][C:24]2[C:23]([CH3:28])([CH3:27])[CH2:22][CH2:21][C:20]([CH3:30])([CH3:29])[C:19]=2[CH:18]=1.[CH2:32](OC[C@H]1[C@@H](C=O)[C@@]1(C)C1C=CC2C(C)(C)CCC(C)(C)C=2C=1)C>>[CH2:1]([O:2][CH2:3][C@H:4]1[C@@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@:5]1([CH3:31])[C:17]1[CH:26]=[CH:25][C:24]2[C:23]([CH3:28])([CH3:27])[CH2:22][CH2:21][C:20]([CH3:30])([CH3:29])[C:19]=2[CH:18]=1)[CH3:32]

Participants

Reactant 2

HCID 86595803HCID 86595803, compound

HCID 131725081HCID 131725081, compound

Product 1

HCID 131725082HCID 131725082, compoundYield 92%

Procedure

Following a procedure similar to that for the preparation of Compound 16a but using Intermediate 13b as the starting material afforded the title compound (44 mg, 92% yield) as a white solid:

Sources & evidence

ORD record: ord-85695249b65c4b19ae364d9a50590edc
Source dataset: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06936636B2

Reaction notes

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