HCID 86759823, compound → HCID 131725083, compound

HRID 586665Notes

Reaction equation

HRID 586665 reaction equation
[CH3:1][O:2][CH2:3][C@@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@@:5]1([CH3:31])[C:17]1[CH:26]=[CH:25][C:24]2[C:23]([CH3:28])([CH3:27])[CH2:22][CH2:21][C:20]([CH3:30])([CH3:29])[C:19]=2[CH:18]=1.COC[C@H]1[C@H](C=O)[C@]1(C)C1C=CC2C(C)(C)CCC(C)(C)C=2C=1>>[CH3:1][O:2][CH2:3][C@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@@:5]1([CH3:31])[C:17]1[CH:26]=[CH:25][C:24]2[C:23]([CH3:28])([CH3:27])[CH2:22][CH2:21][C:20]([CH3:30])([CH3:29])[C:19]=2[CH:18]=1

Participants

3

Reactant 2

HCID 86759823HCID 86759823, compoundHCID 131725081HCID 131725081, compound

Product 1

HCID 131725083HCID 131725083, compoundYield 76%

Procedure

Following a procedure similar to that for the preparation of Compound 16a but using Intermediate 14a as the starting material afforded the title compound (32 mg, 76% yield) as a white solid:

Sources & evidence

ORD record
ord-751e93bf6da84d539ca525afe67b5239
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

Loading…