HCID 131725084, compound → HCID 131725091, compound

HRID 586673Notes

Reaction equation

COC[C@@H]1[C@H](/C=C/C(/C)=C/C(O)=O)[C@@]1(C)C1C=CC2C(C)(C)CCC(C)(C)C=2C=1.[CH2:30]([O:32][CH2:33][C@H:34]1[C@H:36](/[CH:37]=[CH:38]/[C:39](/[CH3:46])=[CH:40]/[C:41]([O:43]CC)=[O:42])[C@@:35]1([CH3:61])[C:47]1[CH:56]=[CH:55][C:54]2[C:53]([CH3:58])([CH3:57])[CH2:52][CH2:51][C:50]([CH3:60])([CH3:59])[C:49]=2[CH:48]=1)[CH3:31]>>[CH2:30]([O:32][CH2:33][C@H:34]1[C@H:36](/[CH:37]=[CH:38]/[C:39](/[CH3:46])=[CH:40]/[C:41]([OH:43])=[O:42])[C@@:35]1([CH3:61])[C:47]1[CH:56]=[CH:55][C:54]2[C:53]([CH3:58])([CH3:57])[CH2:52][CH2:51][C:50]([CH3:60])([CH3:59])[C:49]=2[CH:48]=1)[CH3:31]

Participants

Reactant 2

HCID 131725084HCID 131725084, compound

HCID 131725087HCID 131725087, compound

Product 1

HCID 131725091HCID 131725091, compoundYield 87%

Procedure

Following a procedure similar to that for the preparation of Compound 20a but using Compound 18b as the starting material afforded the title compound (31 mg, 87% yield) as a white solid:

Sources & evidence

ORD record: ord-6b3f167f86924728b27bbe7c1b6adfc2
Source dataset: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06936636B2

Reaction notes

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