HCID 131725085, compound → HCID 131725092, compound

HRID 586674Notes

Reaction equation

HRID 586674 reaction equation
[CH3:1][O:2][CH2:3][C@@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:14])=[CH:10]/[C:11]([OH:13])=[O:12])[C@@:5]1([CH3:29])[C:15]1[CH:24]=[CH:23][C:22]2[C:21]([CH3:26])([CH3:25])[CH2:20][CH2:19][C:18]([CH3:28])([CH3:27])[C:17]=2[CH:16]=1.COC[C@@H]1[C@@H](/C=C/C(/C)=C/C(OCC)=O)[C@]1(C)C1C=CC2C(C)(C)CCC(C)(C)C=2C=1>>[CH3:1][O:2][CH2:3][C@@H:4]1[C@@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:14])=[CH:10]/[C:11]([OH:13])=[O:12])[C@:5]1([CH3:29])[C:15]1[CH:24]=[CH:23][C:22]2[C:21]([CH3:26])([CH3:25])[CH2:20][CH2:19][C:18]([CH3:28])([CH3:27])[C:17]=2[CH:16]=1

Participants

3

Reactant 2

HCID 131725085HCID 131725085, compoundHCID 131725087HCID 131725087, compound

Product 1

HCID 131725092HCID 131725092, compoundYield 80%

Procedure

Following a procedure similar to that for the preparation of Compound 20a but using Compound 19a as the starting material afforded the title compound (26 mg, 80% yield) as a white solid:

Sources & evidence

ORD record
ord-cb168e57de834d43a14697e6976d06bd
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

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