HCID 131725086, compound → HCID 131725093, compound

HRID 586675Notes

Reaction equation

COC[C@@H]1[C@H](/C=C/C(/C)=C/C(O)=O)[C@@]1(C)C1C=CC2C(C)(C)CCC(C)(C)C=2C=1.[CH2:30]([O:32][CH2:33][C@@H:34]1[C@@H:36](/[CH:37]=[CH:38]/[C:39](/[CH3:46])=[CH:40]/[C:41]([O:43]CC)=[O:42])[C@:35]1([CH3:61])[C:47]1[CH:56]=[CH:55][C:54]2[C:53]([CH3:58])([CH3:57])[CH2:52][CH2:51][C:50]([CH3:60])([CH3:59])[C:49]=2[CH:48]=1)[CH3:31]>>[CH2:30]([O:32][CH2:33][C@@H:34]1[C@@H:36](/[CH:37]=[CH:38]/[C:39](/[CH3:46])=[CH:40]/[C:41]([OH:43])=[O:42])[C@:35]1([CH3:61])[C:47]1[CH:56]=[CH:55][C:54]2[C:53]([CH3:58])([CH3:57])[CH2:52][CH2:51][C:50]([CH3:60])([CH3:59])[C:49]=2[CH:48]=1)[CH3:31]

Participants

Reactant 2

HCID 131725086HCID 131725086, compound

HCID 131725087HCID 131725087, compound

Product 1

HCID 131725093HCID 131725093, compoundYield 80%

Procedure

Following a procedure similar to that for the preparation of Compound 20a but using Compound 19b as the starting material afforded the title compound (26 mg, 80% yield) as a white solid:

Sources & evidence

ORD record: ord-7e708aa388ce4e4db223c6ac1f557bb4
Source dataset: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06936636B2

Reaction notes

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