HCID 86595806, compound → HCID 86595808, compound

HRID 586684Notes

Reaction equation

COC[C@@H]1[C@H](C=O)[C@]1(C)C1C=C(C(C)C)C=C(C(C)C)C=1.CC12C(C)(C)[C:26]([C:32]([O:34][CH2:35][C@H:36]3[C@H:38]([CH2:39][O:40]CC)[C@@:37]3([CH3:55])[C:43]3[CH:48]=[C:47]([CH:49]([CH3:51])[CH3:50])[CH:46]=[C:45]([CH:52]([CH3:54])[CH3:53])[CH:44]=3)=O)(CC1)OC2=O>>[CH2:32]([O:34][CH2:35][C@H:36]1[C@H:38]([CH:39]=[O:40])[C@:37]1([CH3:55])[C:43]1[CH:44]=[C:45]([CH:52]([CH3:53])[CH3:54])[CH:46]=[C:47]([CH:49]([CH3:51])[CH3:50])[CH:48]=1)[CH3:26]

Participants

Reactant 2

HCID 86595806HCID 86595806, compound

HCID 86595809HCID 86595809, compound

Product 1

HCID 86595808HCID 86595808, compoundYield 83%

Procedure

Following a procedure similar to that for the preparation of Intermediate 45 but using Intermediate 43b as the starting material afforded the title compound (30 mg, 83% yield) as a colorless oil:

Sources & evidence

ORD record: ord-6f5b3a3e6c4b463d9d30bba29131b4d7
Source dataset: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06936636B2

Reaction notes

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