HCID 59981098, compound → HCID 59981136, compound

HRID 586685Notes

Reaction equation

HRID 586685 reaction equation
[CH3:1][O:2][CH2:3][C@@H:4]1[C@H:6]([CH:7]=[O:8])[C@:5]1([CH3:21])[C:9]1[CH:14]=[C:13]([CH:15]([CH3:17])[CH3:16])[CH:12]=[C:11]([CH:18]([CH3:20])[CH3:19])[CH:10]=1.CC12C(C)(C)C(C(OC[C@@H]3[C@@H](COC)[C@]3(C)C3C=C(C(C)C)C=C(C(C)C)C=3)=O)(CC1)OC2=O>>[CH3:1][O:2][CH2:3][C@@H:4]1[C@@H:6]([CH:7]=[O:8])[C@@:5]1([CH3:21])[C:9]1[CH:10]=[C:11]([CH:18]([CH3:19])[CH3:20])[CH:12]=[C:13]([CH:15]([CH3:17])[CH3:16])[CH:14]=1

Participants

3

Reactant 2

HCID 59981098HCID 59981098, compoundHCID 86595809HCID 86595809, compound

Product 1

HCID 59981136HCID 59981136, compoundYield 87%

Procedure

Following a procedure similar to that for the preparation of Intermediate 45 but using Intermediate 44a as the starting material afforded the title compound (14 mg, 87% yield) as a colorless oil:

Sources & evidence

ORD record
ord-913c3077459d4f34b22ac230631ae6dd
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

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