HCID 59981119, compound → HCID 131725096, compound

HRID 586689Notes

Reaction equation

HRID 586689 reaction equation
[CH3:1][O:2][CH2:3][C@@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@@:5]1([CH3:29])[C:17]1[CH:22]=[C:21]([CH:23]([CH3:25])[CH3:24])[CH:20]=[C:19]([CH:26]([CH3:28])[CH3:27])[CH:18]=1.COC[C@H]1[C@H](C=O)[C@]1(C)C1C=C(C(C)C)C=C(C(C)C)C=1>>[CH3:1][O:2][CH2:3][C@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@@:5]1([CH3:29])[C:17]1[CH:18]=[C:19]([CH:26]([CH3:27])[CH3:28])[CH:20]=[C:21]([CH:23]([CH3:25])[CH3:24])[CH:22]=1

Participants

3

Reactant 2

HCID 59981119HCID 59981119, compoundHCID 131725094HCID 131725094, compound

Product 1

HCID 131725096HCID 131725096, compoundYield 85%

Procedure

Following a procedure similar to that for the preparation of Compound 24 but using Intermediate 47a as the starting material afforded the title compound (19 mg, 85% yield) as a white solid:

Sources & evidence

ORD record
ord-608502f3cfb340018015e3d58f992a46
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

Loading…