HCID 86595810, compound → HCID 131725098, compound

HRID 586691Notes

Reaction equation

HRID 586691 reaction equation
[CH3:1][O:2][CH2:3][C@@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@@:5]1([CH3:29])[C:17]1[CH:22]=[C:21]([CH:23]([CH3:25])[CH3:24])[CH:20]=[C:19]([CH:26]([CH3:28])[CH3:27])[CH:18]=1.[CH2:30](OC[C@@H]1[C@@H](C=O)[C@@]1(C)C1C=C(C(C)C)C=C(C(C)C)C=1)C>>[CH2:1]([O:2][CH2:3][C@@H:4]1[C@@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:16])=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[C@:5]1([CH3:29])[C:17]1[CH:18]=[C:19]([CH:26]([CH3:28])[CH3:27])[CH:20]=[C:21]([CH:23]([CH3:24])[CH3:25])[CH:22]=1)[CH3:30]

Participants

3

Reactant 2

HCID 86595810HCID 86595810, compoundHCID 131725094HCID 131725094, compound

Product 1

HCID 131725098HCID 131725098, compoundYield 73%

Procedure

Following a procedure similar to that for the preparation of Compound 24 but using Intermediate 48b as the starting material afforded the title compound (36 mg, 73% yield) as a white solid:

Sources & evidence

ORD record
ord-5f5b95eff8d640fc9418f683eb8e9cb8
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

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