HCID 131725096, compound → HCID 131725101, compound

HRID 586694Notes

Reaction equation

HRID 586694 reaction equation
[CH3:1][O:2][CH2:3][C@@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:14])=[CH:10]/[C:11]([OH:13])=[O:12])[C@@:5]1([CH3:27])[C:15]1[CH:20]=[C:19]([CH:21]([CH3:23])[CH3:22])[CH:18]=[C:17]([CH:24]([CH3:26])[CH3:25])[CH:16]=1.COC[C@H]1[C@H](/C=C/C(/C)=C/C(OCC)=O)[C@@]1(C)C1C=C(C(C)C)C=C(C(C)C)C=1>>[CH3:1][O:2][CH2:3][C@H:4]1[C@H:6](/[CH:7]=[CH:8]/[C:9](/[CH3:14])=[CH:10]/[C:11]([OH:13])=[O:12])[C@@:5]1([CH3:27])[C:15]1[CH:16]=[C:17]([CH:24]([CH3:25])[CH3:26])[CH:18]=[C:19]([CH:21]([CH3:23])[CH3:22])[CH:20]=1

Participants

3

Reactant 2

HCID 131725096HCID 131725096, compoundHCID 131725099HCID 131725099, compound

Product 1

HCID 131725101HCID 131725101, compoundYield 47%

Procedure

Following a procedure similar to that for the preparation of Compound 28 but using Compound 26a as the starting material afforded the title compound (8 mg, 47% yield) as a white solid:

Sources & evidence

ORD record
ord-2c113ba040514c1fac804fb3dbc5f758
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

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