HCID 131725099, compound → HCID 131725102, compound

HRID 586695Notes

Reaction equation

HRID 586695 reaction equation
COC[C@@H]1[C@H](/C=C/C(/C)=C/C(O)=O)[C@@]1(C)C1C=C(C(C)C)C=C(C(C)C)C=1.[CH2:28]([O:30][CH2:31][C@H:32]1[C@H:34](/[CH:35]=[CH:36]/[C:37](/[CH3:44])=[CH:38]/[C:39]([O:41]CC)=[O:40])[C@@:33]1([CH3:57])[C:45]1[CH:50]=[C:49]([CH:51]([CH3:53])[CH3:52])[CH:48]=[C:47]([CH:54]([CH3:56])[CH3:55])[CH:46]=1)[CH3:29]>>[CH2:28]([O:30][CH2:31][C@H:32]1[C@H:34](/[CH:35]=[CH:36]/[C:37](/[CH3:44])=[CH:38]/[C:39]([OH:41])=[O:40])[C@@:33]1([CH3:57])[C:45]1[CH:46]=[C:47]([CH:54]([CH3:55])[CH3:56])[CH:48]=[C:49]([CH:51]([CH3:53])[CH3:52])[CH:50]=1)[CH3:29]

Participants

3

Reactant 2

HCID 131725099HCID 131725099, compoundHCID 131725103HCID 131725103, compound

Product 1

HCID 131725102HCID 131725102, compoundYield 84%

Procedure

Following a procedure similar to that for the preparation of Compound 28 but using Compound 26b as the starting material afforded the title compound (29 mg, 84% yield) as a white solid:

Sources & evidence

ORD record
ord-d36f131a1dc047d690c32e5255b41ed1
Source dataset
uspto-grants-2005_08
Patent number
US06936636B2

Reaction notes

Loading…