5-Fluoro-2-nitrotoluene → HCID 10118006, compound

HRID 586771Notes

Reaction equation

HRID 586771 reaction equation
[NH2:1][C:2](=[N:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]2[CH2:20][CH2:19][N:18]([C:21]([NH:23][CH2:24][CH2:25][CH2:26][CH2:27][CH:28]3[CH2:32][CH2:31][S:30][S:29]3)=[O:22])[CH2:17][CH2:16]2)=[C:11](C)[CH:10]=1)[C:3]1[S:4][CH:5]=[CH:6][CH:7]=1.F[C:35]1C=CC([N+]([O-])=O)=C(C)C=1>>[NH2:1][C:2](=[N:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]2[CH2:16][CH2:17][N:18]([C:21]([NH:23][CH2:24][CH2:25][CH2:26][CH2:27][CH:28]3[CH2:32][CH2:31][S:30][S:29]3)=[O:22])[CH2:19][CH2:20]2)=[CH:11][C:10]=1[CH3:35])[C:3]1[S:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 949565-Fluoro-2-nitrotolueneHCID 10185551HCID 10185551, compound

Product 1

HCID 10118006HCID 10118006, compoundYield 16%

Procedure

The experimental protocol used is the same as that described for the compound of Example 6, 5-fluoro-2-nitrotoluene replacing 2-fluoro-5-nitrotoluene. A white solid product is obtained (yield 16%). Melting point: 169.4-170.9° C.

Workup

  1. customA white solid product is obtained (yield 16%)

Sources & evidence

ORD record
ord-5c33ae1cf30b437ba257b11dc1fc504b
Source dataset
uspto-grants-2005_08
Patent number
US06936715B2

Reaction notes

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