2-Chloro-5-nitroanisole → HCID 10208173, compound

HRID 586772Notes

Reaction equation

HRID 586772 reaction equation
[NH2:1][C:2](=[N:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]2[CH2:20][CH2:19][N:18]([C:21]([NH:23][CH2:24][CH2:25][CH2:26][CH2:27][CH:28]3[CH2:32][CH2:31][S:30][S:29]3)=[O:22])[CH2:17][CH2:16]2)=[C:11](C)[CH:10]=1)[C:3]1[S:4][CH:5]=[CH:6][CH:7]=1.ClC1C=CC([N+]([O-])=O)=C[C:36]=1[O:44]C>>[NH2:1][C:2](=[N:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]2[CH2:20][CH2:19][N:18]([C:21]([NH:23][CH2:24][CH2:25][CH2:26][CH2:27][CH:28]3[CH2:32][CH2:31][S:30][S:29]3)=[O:22])[CH2:17][CH2:16]2)=[C:11]([O:44][CH3:36])[CH:10]=1)[C:3]1[S:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 705192-Chloro-5-nitroanisoleHCID 10185551HCID 10185551, compound

Product 1

HCID 10208173HCID 10208173, compoundYield 25%

Procedure

The experimental protocol used is the same as that described for the compound of Example 6, 2-chloro-5-nitroanisole replacing 2-fluoro-5-nitrotoluene. A pale yellow solid product is obtained (yield 25%). Melting point: 185.6-186.3° C.

Workup

  1. customA pale yellow solid product is obtained (yield 25%)

Sources & evidence

ORD record
ord-afa0360cd9ff4c3583e608cc84b57eaf
Source dataset
uspto-grants-2005_08
Patent number
US06936715B2

Reaction notes

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