反应详情

A solution of 4-butoxybenzene-1,3-diamine dihydrochloride in 4.2 ml of 0.25N sodium hydroxide is added to a solution of 2-[ethyl(4-nitrosophenyl)amino]ethanol in 4.2 ml of water at 50° C. After 3 hours at 50° C., the supernatant is removed and the residual gum is washed with water and then taken up in isopropyl ether. The solid formed is filtered off and dried. 360 mg of 2-{[4-(2-amino-5-ethoxy-4-imino cyclohexa-2,5-dienylideneamino)phenyl]-ethylamino}ethanol hydrochloride 65 are thus obtained in the form of a black powder.

1. customthe supernatant is removed
2. washthe residual gum is washed with water
3. customThe solid formed
4. filtrationis filtered off
5. customdried