tert-butyl N-((piperidin-2-yl)methyl)carbamate → Tert-butyl [(1-(4-((3-(sulfamoylmethyl)phenyl)amino)-1,3,5-triazin-2-yl)piperidine-2-yl)methyl]carbamate

Participants

Role	Name	HCID	Charge
Reactant	tert-butyl N-((piperidin-2-yl)methyl)carbamate	HCID 2756031	—
Reactant	rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide	HCID 60197106	—
Reactant	3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide	HCID 86679822	—
Product	Tert-butyl [(1-(4-((3-(sulfamoylmethyl)phenyl)amino)-1,3,5-triazin-2-yl)piperidine-2-yl)methyl]carbamate	HCID 60197197	—

Reaction Steps

B7 was prepared following the procedure reported for B4 using A1 and rac-tert-butyl (piperidin-2-yl)methylcarbamate and obtained as a white crystalline solid; yield: 280 mg (65%). MS (ES) C21H31N7O4S requires: 477. found: 478 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09226929B2
Source dataset	uspto-grants-2016_01
ORD ID	ord-f379f6e7cd824fd297cc9dee8346742e
Source note	uspto-grants-2016_01