Dimethyl-(2-piperidin-2-yl-ethyl)-amine → rac-3-[(4-(2-(2-(Dimethylamino)ethyl)piperidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

Participants

Role	Name	HCID	Charge
Reactant	Dimethyl-(2-piperidin-2-yl-ethyl)-amine	HCID 296295	—
Reactant	rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide	HCID 60197106	—
Reactant	3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide	HCID 86679822	—
Product	rac-3-[(4-(2-(2-(Dimethylamino)ethyl)piperidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide	HCID 60197198	—

Reaction Steps

B8 was prepared following the procedure reported for B4 using A1 and rac-2-(2-(dimethylamino)ethyl)piperidine and obtained as a white crystalline solid; yield: 230 mg (61%). MS (ES) C19H29N7O2S requires: 419. found: 420 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09226929B2
Source dataset	uspto-grants-2016_01
ORD ID	ord-3db4b5041afa430ca6e166688b695d9f
Source note	uspto-grants-2016_01