(R)-2-Methylpyrrolidine → HCID 60197302, compound

HRID 587150Notes

Reaction equation

HRID 587150 reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:10]=[C:11]([CH2:15][S:16]([NH2:19])(=[O:18])=[O:17])[CH:12]=[CH:13][CH:14]=2)[N:3]=1.[CH3:20][C@@H:21]1[CH2:25][CH2:24][CH2:23][NH:22]1>>[CH3:20][C@@H:21]1[CH2:25][CH2:24][CH2:23][N:22]1[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:10]=[C:11]([CH2:15][S:16]([NH2:19])(=[O:18])=[O:17])[CH:12]=[CH:13][CH:14]=2)[N:3]=1

Participants

3

Reactant 2

HCID 641544(R)-2-MethylpyrrolidineHCID 866798223-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

Product 1

HCID 60197302HCID 60197302, compound

Procedure

B15 was prepared following the general procedure reported for B10 using A1 and (R)-2-methylpyrrolidine. Yield: 31.5 mg (9%), colorless amorphous solid. MS (ES) C15H20N6O2S requires: 348. found: 349 (M+H)+.

Workup

  1. customB15 was prepared

Sources & evidence

ORD record
ord-56d15c77a9554388a656b341305bdd3f
Source dataset
uspto-grants-2016_01
Patent number
US09226929B2

Reaction notes

Loading…