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HRID587151

反应详情

EQUATION

反应方程式

HRID 587151 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)[C@@H]1CCCN1
HCID2782840

(s)-2-(trifluoromethyl)pyrrolidine

C5H8F3N

结构：NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1
HCID86679822

未命名化合物

PRODUCTS

生成物

1
结构：NS(=O)(=O)Cc1cccc(Nc2ncnc(N3CCC[C@H]3C(F)(F)F)n2)c1
HCID60197303

未命名化合物

PROCEDURE

实验过程

B16 was prepared following the general procedure reported for B10 using A1 and (S)-2-(trifluoromethyl)pyrrolidine. The title compound (B16) was purified by reverse phase RP-HPLC (column: C18), using H2O (0.1% TFA) and MeOH (0.1% TFA) as eluents. Yield: 58.7 mg (15%), colorless amorphous solid. MS (ES) C15H17F3N6O2S requires: 402. found: 403 (M+H)+.

WORKUP

后处理

  1. customB16 was prepared
  2. customThe title compound (B16) was purified by reverse phase RP-HPLC (column: C18)