2-(2-phenylethyl)pyrrolidine → HCID 60197408, compound

HRID 587160Notes

Reaction equation

HRID 587160 reaction equation
CO[CH2:3][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][N:5]1[C:10]1[N:15]=[CH:14][N:13]=[C:12]([NH:16][C:17]2[CH:18]=[C:19]([CH2:23][S:24]([NH2:27])(=[O:26])=[O:25])[CH:20]=[CH:21][CH:22]=2)[N:11]=1.ClC1N=CN=C(N[C:36]2[CH:37]=[C:38](CS(N)(=O)=O)[CH:39]=[CH:40][CH:41]=2)N=1.C1(CCC2CCCN2)C=CC=CC=1>>[C:36]1([CH2:8][CH2:9][CH:4]2[CH2:3][CH2:7][CH2:6][N:5]2[C:10]2[N:15]=[CH:14][N:13]=[C:12]([NH:16][C:17]3[CH:18]=[C:19]([CH2:23][S:24]([NH2:27])(=[O:26])=[O:25])[CH:20]=[CH:21][CH:22]=3)[N:11]=2)[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=1

Participants

4

Reactant 3

HCID 37222722-(2-phenylethyl)pyrrolidineHCID 60197106rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamideHCID 866798223-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

Product 1

HCID 60197408HCID 60197408, compound

Procedure

B27 was prepared following the procedure reported for B4 using A1 and rac-2-(2-phenylethyl)pyrrolidine and obtained as a white crystalline solid; yield: 140 mg (35%). MS (ES) C22H26N6O2S requires: 438. found: 439 (M+H)+.

Workup

  1. customB27 was prepared
  2. customobtained as a white crystalline solid

Sources & evidence

ORD record
ord-a0736a39bbef4fe98b9f93c1777ccad5
Source dataset
uspto-grants-2016_01
Patent number
US09226929B2

Reaction notes

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