2-Phenylpyrrolidine → HCID 60197505, compound

Participants

Role	Name	HCID	Charge
Reactant	2-Phenylpyrrolidine	HCID 261892	—
Reactant	rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide	HCID 60197106	—
Reactant	3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide	HCID 86679822	—
Product	HCID 60197505	HCID 60197505	—

Reaction Steps

B33 was prepared following the procedure reported for B4 using A1 and rac-2-phenylpyrrolidine, and it was obtained as a white powder; yield: 90 mg (24%). 1H NMR (300 MHz, d6-DMSO, 300K) δ 1.77-2.05 (m, 3H), 2.26-2.48 (m, 1H), 3.61-3.80 (m, 1H), 3.80-3.98 (m, 1H), 4.07 and 4.22 (2 s, 2H), 5.28 and 5.30 (2 s, 1H), 6.75-6.92 (m, 3H), 6.94-7.07 (m, 1H), 7.09-7.42 (m, 6H), 7.70 and 7.90 (2 s, 1H), 8.06 and 8.27 (2 s, 1H), 9.55 and 9.72 (2bs, 1H). MS (ES) C20H22N6O2S requires: 410. found: 411 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09226929B2
Source dataset	uspto-grants-2016_01
ORD ID	ord-c5e7021adc094acaa354532c727437ec
Source note	uspto-grants-2016_01