rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide → HCID 60197598, compound

HRID 587167Notes

Reaction equation

HRID 587167 reaction equation
[CH3:1][O:2][CH2:3][CH:4]1[CH2:9][CH2:8]CC[N:5]1[C:10]1[N:15]=[CH:14][N:13]=[C:12]([NH:16][C:17]2[CH:18]=[C:19]([CH2:23][S:24]([NH2:27])(=[O:26])=[O:25])[CH:20]=[CH:21][CH:22]=2)[N:11]=1.ClC1N=CN=C(NC2C=C(CS(N)(=O)=O)C=CC=2)N=1.Cl.COC[C@H]1CCN1>>[CH3:1][O:2][CH2:3][C@H:4]1[CH2:9][CH2:8][N:5]1[C:10]1[N:15]=[CH:14][N:13]=[C:12]([NH:16][C:17]2[CH:18]=[C:19]([CH2:23][S:24]([NH2:27])(=[O:25])=[O:26])[CH:20]=[CH:21][CH:22]=2)[N:11]=1

Participants

4

Reactant 3

HCID 60197106rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamideHCID 682877611396710-21-6HCID 866798223-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

Product 1

HCID 60197598HCID 60197598, compound

Procedure

B35 was prepared following the general procedure reported for B4 using A1 and A6 and obtained as white crystals; yield: 85 mg (26%). MS (ES) C15H20N6O3S requires: 364. found: 365 (M+H)+.

Workup

  1. customB35 was prepared
  2. customobtained as white crystals

Sources & evidence

ORD record
ord-f25209bbd42e4587b8df3dfab4421f91
Source dataset
uspto-grants-2016_01
Patent number
US09226929B2

Reaction notes

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