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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587595Generated: October 30, 2026

4-Nitroaniline → ethyl {2-[(4-nitrophenyl)amino]-3H-imidazo[4,5-b]pyridin-3-yl}acetate

https://huagongshe.com/reaction/587595

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-NitroanilineHCID 7475—
ReactantHCID 58577766HCID 58577766—
Productethyl {2-[(4-nitrophenyl)amino]-3H-imidazo[4,5-b]pyridin-3-yl}acetateHCID 70168453101.2%

Reaction Conditions

Temperature150 °C

Reaction Steps

A mixture of ethyl (2-chloro-3H-imidazo[4,5-b]pyridin-3-yl)acetate (2.8 g) and 4-nitroaniline (1.6 g) was stirred at 150° C. for 1 h to give the title compound (4.0 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09226921B2
Source datasetuspto-grants-2016_01
ORD IDord-84e346f135e4437b9e1b2b8aad98de7e
Source noteuspto-grants-2016_01