HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587595Generated: October 30, 2026
4-Nitroaniline → ethyl {2-[(4-nitrophenyl)amino]-3H-imidazo[4,5-b]pyridin-3-yl}acetate
https://huagongshe.com/reaction/587595
Participants
| Role | Name | HCID | Charge |
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| Reactant | 4-Nitroaniline | HCID 7475 | — |
| Reactant | HCID 58577766 | HCID 58577766 | — |
| Product | ethyl {2-[(4-nitrophenyl)amino]-3H-imidazo[4,5-b]pyridin-3-yl}acetate | HCID 70168453 | 101.2% |
Reaction Steps
A mixture of ethyl (2-chloro-3H-imidazo[4,5-b]pyridin-3-yl)acetate (2.8 g) and 4-nitroaniline (1.6 g) was stirred at 150° C. for 1 h to give the title compound (4.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09226921B2 |
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| Source dataset | uspto-grants-2016_01 |
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| ORD ID | ord-84e346f135e4437b9e1b2b8aad98de7e |
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| Source note | uspto-grants-2016_01 |
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