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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587616Generated: October 29, 2026

2-(5-methylpyridin-2-yl)-5-nitro-2H-indazole → HCID 67126077, compound

https://huagongshe.com/reaction/587616

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-methylpyridin-2-yl)-5-nitro-2H-indazoleHCID 67126051—
ReactantHCID 67126947HCID 67126947—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 67126077HCID 67126077—

Reaction Steps

The mixture of 1-(5-methylpyridin-2-yl)-5-nitro-1H-indazole and 2-(5-methylpyridin-2-yl)-5-nitro-2H-indazole was dissolved in EtOH (20 mL), and 10% Pd/C (250 mg) was added. Under H2 atmosphere, the mixture was stirred at room temperature for 12 h, filtered and concentrated in vacuo. The residue was chromatographed on silica gel eluting with AcOEt/Hexane to give the title compound (61 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09226921B2
Source datasetuspto-grants-2016_01
ORD IDord-da000dbf5cf345e0b3b839590a81e7ad
Source noteuspto-grants-2016_01