Trifluoroacetic acid → HCID 66788310, compound

Participants

Reaction Steps

To a stirred solution of D100 (0.207 g, 0.560 mmol) in dry DCM (3.5 ml), was added trifluoroacetic acid (1.01 ml). The mixture was stirred at r.t. for 2 h and then concentrated in vacuo. The residue was basified with NaOH 50% (aqueous solution) and extracted with DCM. The organic phase was separated, dried (Na2SO4) and concentrated in vacuo to yield intermediate D101 (0.149 g, 99%).

Provenance & Evidence