HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-[2-(methylamino)ethyl]benzoate → Methyl 4-(2-((4-(3,4-dimethoxyphenyl)-4-(methoxycarbonyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-[2-(methylamino)ethyl]benzoate | HCID 21623940 | — |
| Reactant | Methyl 5-chloro-2-(3,4-dimethoxyphenyl)-2-isopropylpentanoate | HCID 59419939 | — |
| Product | Methyl 4-(2-((4-(3,4-dimethoxyphenyl)-4-(methoxycarbonyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate | HCID 25129274 | — |
Reaction Steps
Reaction of 1e with 2b produced 3h. MS found M+H=486. The oxalate salt of 3h was recrystallized from ethyl acetate; mp 129-131° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227918B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-37c5bec93b194824a0ee86396a397bc2 |
| Source note | uspto-grants-2016_01 |