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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587946Generated: October 30, 2026

Methyl 4-[2-(methylamino)ethyl]benzoate → Methyl 4-(2-((4-(3,4-dimethoxyphenyl)-4-(methoxycarbonyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate

https://huagongshe.com/reaction/587946

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-[2-(methylamino)ethyl]benzoateHCID 21623940—
ReactantMethyl 5-chloro-2-(3,4-dimethoxyphenyl)-2-isopropylpentanoateHCID 59419939—
ProductMethyl 4-(2-((4-(3,4-dimethoxyphenyl)-4-(methoxycarbonyl)-5-methylhexyl)(methyl)amino)ethyl)benzoateHCID 25129274—

Reaction Steps

Reaction of 1e with 2b produced 3h. MS found M+H=486. The oxalate salt of 3h was recrystallized from ethyl acetate; mp 129-131° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227918B2
Source datasetuspto-grants-2016_01
ORD IDord-37c5bec93b194824a0ee86396a397bc2
Source noteuspto-grants-2016_01