HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-[2-(methylamino)ethyl]benzoate → Methyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methoxy-5-oxopentyl)(methyl)amino)ethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-[2-(methylamino)ethyl]benzoate | HCID 21623940 | — |
| Reactant | Methyl 5-bromo-2-cyano-2-(3,4-dimethoxyphenyl)pentanoate | HCID 59419915 | — |
| Product | Methyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methoxy-5-oxopentyl)(methyl)amino)ethyl)benzoate | HCID 25129275 | — |
Reaction Steps
Reaction of 1b with 2b produced 3i. MS found M+H=469. The oxalate salt of 3i was recrystallized from ethyl acetate; mp 80-83° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227918B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-77d5150e9b404da6bbb5d565e2384390 |
| Source note | uspto-grants-2016_01 |