Methyl 5-bromo-2-cyano-2-(3,4-dimethoxyphenyl)pentanoate → Ethyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methoxy-5-oxopentyl)(methyl)amino)ethyl)benzoate

Participants

Role	Name	HCID	Charge
Reactant	Methyl 5-bromo-2-cyano-2-(3,4-dimethoxyphenyl)pentanoate	HCID 59419915	—
Reactant	Ethyl 4-(2-(methylamino)ethyl)benzoate	HCID 59419931	—
Product	Ethyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methoxy-5-oxopentyl)(methyl)amino)ethyl)benzoate	HCID 25131640	—

Reaction of 1b with 2c produced 3n. MS found M+H=483. The oxalate salt of 3n was recrystallized from ethyl acetate; mp 88-89° C.