HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-(2-(methylamino)ethyl)benzoate → Ethyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-ethoxy-5-oxopentyl)(methyl)amino)ethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-(2-(methylamino)ethyl)benzoate | HCID 59419931 | — |
| Reactant | Ethyl 5-bromo-2-cyano-2-(3,4-dimethoxyphenyl)pentanoate | HCID 59419942 | — |
| Product | Ethyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-ethoxy-5-oxopentyl)(methyl)amino)ethyl)benzoate | HCID 25129620 | — |
Reaction Steps
Reaction of 1c with 2c produced 3q. MS found M+H=497. The oxalate salt of 3q was recrystallized from ethyl acetate; mp 83-84° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227918B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-e697b8ee7fcc4b78b8bbf2105924b676 |
| Source note | uspto-grants-2016_01 |