HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile → Ethyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile | HCID 13535571 | — |
| Reactant | Ethyl 4-(2-(methylamino)ethyl)benzoate | HCID 59419931 | — |
| Product | Ethyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate | HCID 25108828 | — |
Reaction Steps
Reaction of 1f with 2c produced 3r. MS found M+H=467. The oxalate salt of 3r was recrystallized from ethyl acetate; mp 111-112° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227918B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-99c7339d6f264f269c706e1234b5b5b5 |
| Source note | uspto-grants-2016_01 |