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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587952Generated: October 25, 2026

5-Bromo-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile → Ethyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate

https://huagongshe.com/reaction/587952

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrileHCID 13535571—
ReactantEthyl 4-(2-(methylamino)ethyl)benzoateHCID 59419931—
ProductEthyl 4-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)(methyl)amino)ethyl)benzoateHCID 25108828—

Reaction Steps

Reaction of 1f with 2c produced 3r. MS found M+H=467. The oxalate salt of 3r was recrystallized from ethyl acetate; mp 111-112° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227918B2
Source datasetuspto-grants-2016_01
ORD IDord-99c7339d6f264f269c706e1234b5b5b5
Source noteuspto-grants-2016_01