HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-bromo-2-cyano-2-(3,4-dimethoxyphenyl)pentanoate → Methyl 3-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methoxy-5-oxopentyl)(methyl)amino)ethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-bromo-2-cyano-2-(3,4-dimethoxyphenyl)pentanoate | HCID 59419915 | — |
| Reactant | Methyl 3-(2-(methylamino)ethyl)benzoate | HCID 59419935 | — |
| Product | Methyl 3-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methoxy-5-oxopentyl)(methyl)amino)ethyl)benzoate | HCID 25129967 | — |
Reaction Steps
Reaction of 1b with 2d produced 3t. MS found M+H=469. The oxalate salt of 3t was recrystallized from ethyl acetate; mp 94-95° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227918B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-32c000a12ec24a30a89837aab9e8b3c7 |
| Source note | uspto-grants-2016_01 |