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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587955Generated: October 30, 2026

Ethyl 4-(2-(methylamino)ethyl)benzoate → Ethyl 4-(2-((4-(3,4-dimethoxyphenyl)-4-(methoxycarbonyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate

https://huagongshe.com/reaction/587955

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-(2-(methylamino)ethyl)benzoateHCID 59419931—
ReactantMethyl 5-chloro-2-(3,4-dimethoxyphenyl)-2-isopropylpentanoateHCID 59419939—
ProductEthyl 4-(2-((4-(3,4-dimethoxyphenyl)-4-(methoxycarbonyl)-5-methylhexyl)(methyl)amino)ethyl)benzoateHCID 25131316—

Reaction Steps

Reaction of 1e with 2c produced 3w. MS found M+H=500. The oxalate salt of 3w was recrystallized from ethyl acetate; mp 121-123° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227918B2
Source datasetuspto-grants-2016_01
ORD IDord-e2099279929a46818900aff177e0f27e
Source noteuspto-grants-2016_01