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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587961Generated: October 27, 2026

Methyl 3-(2-(methylamino)ethyl)benzoate → Methyl 3-(2-((4-(3,4-dimethoxyphenyl)-4-(methoxycarbonyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate

https://huagongshe.com/reaction/587961

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(2-(methylamino)ethyl)benzoateHCID 59419935—
ReactantMethyl 5-chloro-2-(3,4-dimethoxyphenyl)-2-isopropylpentanoateHCID 59419939—
ProductMethyl 3-(2-((4-(3,4-dimethoxyphenyl)-4-(methoxycarbonyl)-5-methylhexyl)(methyl)amino)ethyl)benzoateHCID 25130667—

Reaction Steps

Reaction of 1e with 2d produced 3aj. MS found M+H=486. The oxalate salt of 3aj was recrystallized from ethyl acetate; mp 87-90° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227918B2
Source datasetuspto-grants-2016_01
ORD IDord-8cb2a99026e34ba3bb15f138fd13345a
Source noteuspto-grants-2016_01