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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 587964Generated: October 27, 2026

Methyl 4-[2-(methylamino)ethyl]benzoate → Methyl 3-(3-cyano-6-((4-(methoxycarbonyl)phenethyl)(methyl)amino)-2-methylhexan-3-yl)benzoate

https://huagongshe.com/reaction/587964

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-[2-(methylamino)ethyl]benzoateHCID 21623940—
ReactantMethyl 3-(6-bromo-3-cyano-2-methylhexan-3-yl)benzoateHCID 59419923—
ProductMethyl 3-(3-cyano-6-((4-(methoxycarbonyl)phenethyl)(methyl)amino)-2-methylhexan-3-yl)benzoateHCID 25130989—

Reaction Steps

Reaction of 1r with 2b produced 3am. MS found M+H=451. The oxalate salt of 3am was recrystallized from methanol/ether; mp 108-112° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227918B2
Source datasetuspto-grants-2016_01
ORD IDord-239a54aa907041eeb508d179f8192e85
Source noteuspto-grants-2016_01