HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 71496163, compound → HCID 71496162, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 71496163 | HCID 71496163 | — |
| Reactant | HCID 71496699 | HCID 71496699 | — |
| Product | HCID 71496162 | HCID 71496162 | 60.8% |
Reaction Steps
The title compound was prepared in the same manner as in Example 21, with the exception that (S)—N-(3-chlorophenyl)-2-(3-piperidylamino)nicotinamide of Example 20-B, instead of N-(3-chlorophenyl)-2-(2,2,6,6-tetramethylpiperidin-4-ylamino)nicotinamide, was used in the same molar amount (Yield: 60.8%). 1H NMR (CDCl3) δ 8.50 (br, 1H), 8.22 (d, 1H), 7.97 (s, 1H), 7.73 (d, 1H), 7.61 (s, 1H), 7.45 (d, 1H), 7.25 (t, 1H), 7.09 (d, 1H), 6.53-6.47 (m, 1H), 4.33 (br, 1H), 3.61 (t, 2H), 2.76-2.45 (m, 6H), 1.85-1.58 (m, 4H) ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227955B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-7da845c388e045bc976e3fb2534d0dfe |
| Source note | uspto-grants-2016_01 |