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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 588055Generated: October 30, 2026

HCID 71496163, compound → HCID 71496162, compound

https://huagongshe.com/reaction/588055

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 71496163HCID 71496163—
ReactantHCID 71496699HCID 71496699—
ProductHCID 71496162HCID 7149616260.8%

Reaction Steps

The title compound was prepared in the same manner as in Example 21, with the exception that (S)—N-(3-chlorophenyl)-2-(3-piperidylamino)nicotinamide of Example 20-B, instead of N-(3-chlorophenyl)-2-(2,2,6,6-tetramethylpiperidin-4-ylamino)nicotinamide, was used in the same molar amount (Yield: 60.8%). 1H NMR (CDCl3) δ 8.50 (br, 1H), 8.22 (d, 1H), 7.97 (s, 1H), 7.73 (d, 1H), 7.61 (s, 1H), 7.45 (d, 1H), 7.25 (t, 1H), 7.09 (d, 1H), 6.53-6.47 (m, 1H), 4.33 (br, 1H), 3.61 (t, 2H), 2.76-2.45 (m, 6H), 1.85-1.58 (m, 4H) ppm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227955B2
Source datasetuspto-grants-2016_01
ORD IDord-7da845c388e045bc976e3fb2534d0dfe
Source noteuspto-grants-2016_01