HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 6-aminonicotinate → HCID 71495430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 6-aminonicotinate | HCID 737487 | — |
| Reactant | 2-Aminomethyl-4-(4-fluorobenzyl)morpholine | HCID 10242735 | — |
| Product | HCID 71495430 | HCID 71495430 | 28.6% |
Reaction Steps
The title compound was prepared in the same manner as in Example 32, with the exception that methyl 6-aminonicotinate, instead of 4-(4-fluorobenzyl)morpholin-2-ylmethylamine, was used in the same molar amount (Total yield: 28.6%). 1H NMR (CDCl3) δ 8.92 (s, 1H), 8.63 (s, 1H), 8.35 (s, 1H), 8.29 (d, 1H), 8.18 (d, 1H), 7.78 (d, 1H), 7.35 (m, 5H), 6.53 (m, 1H), 4.13 (m, 1H), 3.97 (s, 3H), 3.56 (s, 2H), 2.86 (d, 2H), 2.28 (t, 2H), 2.09 (d, 2H), 1.65 (m, 2H) ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227955B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-6a434f7fbbcb4801813057e2a6db2607 |
| Source note | uspto-grants-2016_01 |